Rams OL Andrew Whitworth's full Walter Payton Man of the Year acceptance speech

Watch highlights of the Los Angeles Rams' best plays as they faced the Buffalo Bills, Atlanta Falcons, Arizona Cardinals & San Francisco 49ers in the first four weeks of the 2022 NFL regular season.

On a short week, Los Angeles Rams general manager Les Snead joins J.B. Long & D'Marco Farr as they give their final thoughts on Monday Night Football and turn their attention to a Week 5 matchup against the Dallas Cowboys in SoFi Stadium.

Rams head coach Sean McVay discusses the latest on C Coleman Shelton, S Jordan Fuller coming out of Monday night's game against the 49ers, the latest on C Brian Allen and LG David Edwards, and what he's seen from the Cowboys so far this season.

Los Angeles Rams quarterback Matthew Stafford discusses what he took away from Monday night's 24-9 loss to the San Francisco 49ers, including his thoughts on his performance and the offense's overall, plus Jeremiah Kolone stepping in at center for the injured Coleman Shelton.

Los Angeles Rams wide receiver Cooper Kupp discusses what he took away from the offense's performance in Monday night's 24-9 loss to the San Francisco 49ers.

Los Angeles Rams linebacker Bobby Wagner talks about what he took away from the defense's performance in Monday night's 24-9 loss to the San Francisco 49ers and his reaction to the fan who ran onto the field during the game.

Watch every catch from Los Angeles Rams wide receiver Cooper Kupp's 122-yard game vs. the San Francisco 49ers from Week 4 of the 2022 NFL Season on Monday Night Football.

Los Angeles Rams head coach Sean McVay speaks on the loss to the San Francisco 49ers and bouncing back on a short week.

Los Angeles Rams quarterback Matthew Stafford converts the 4th down with a 13-yard dart to wide receiver Cooper Kupp against the San Francisco 49ers.

Los Angeles Rams wide receiver Cooper Kupp masterfully makes a catch on the sideline for an 18-yard gain against the San Francisco 49ers.

Watch Los Angeles Rams defensive lineman Aaron Donald's full interview on Monday Night countdown. He relives Super Bowl LVI and talks about what he's still looking to accomplish in his career. (Monday Night Countdown/ESPN)

Trailer del juego — Los Rams de Los Angeles contra los 49ers de San Francisco se enfrentan el 3 de octubre a la 5:15 p.m. PT.

Last season, the Los Angeles Rams kicked the San Francisco 49ers out of their house. Now, it's time to go win at theirs. The Rams take on the 49ers for a divisional showdown on October 3rd at 5:15pm on Monday Night Football.

Rams DB Jalen Ramsey discusses facing QB Jimmy Garoppolo and the 49ers offense in Week 4 and his thoughts on player safety in wake of what happened to Dolphins QB Tua Tagovailoa on Thursday night.

Rams head coach Sean McVay discusses the statuses of C Brian Allen, DB Cobie Durant, CB David Long Jr. and LG David Edwards heading Monday night's game at the 49ers, plus his thoughts on the importance of player safety to him.

Troy Santiago nos platica sobre los 3 jugadores a tener en cuenta esta semana contra San Francisco.

Troy Santiago y Ricardo López comentan que los Rams llegan en mejor forma que los 49ers para su partido de Monday Night Football

Rams defensive coordinator Raheem Morris talks about what he's seen from DB Jalen Ramsey in terms of both his play and leadership within the secondary over the last two weeks and the key to repeating the way they were able to contain the 49ers run game in the NFC Championship.

Rams DL Aaron Donald discusses the challenges presented by QB Jimmy Garoppolo and the 49ers offense and the added motivation from playing against a divisional rival.

Rams offensive coordinator Liam Coen talks about what he's seen from the 49ers defense so far and how the team can generating a consist run game.

Watch clips from the Los Angeles Rams Week 4 practices as Rams prepare for Monday Night Football against the San Francisco 49ers.

Rams WR Allen Robinson II talks about the challenges presented by the 49ers secondary and where he feels he's at personally through his first three games as a Ram.

Rams QB Matthew Stafford discusses what he's seen from the 49ers defense so far this season and how it feels to be going against a divisional rival on Monday Night Football.

Rams head coach Sean McVay discusses the latest on the statuses of CB David Long Jr., DB Derion Kendrick, RT Rob Havenstein, DB Cobie Durant and C Brian Allen heading into Week 4 against the 49ers and the expected impact LB Bobby Wagner will have based on his familiarity with the 49ers.

Rams LB Bobby Wagner discusses why he's had success against the 49ers in previous years and what's stood out about DB Jalen Ramsey leading the secondary amid injuries to that group.