HIGHLIGHTS: Matthew Stafford's best throws from 4-touchdown game vs. 49ers in Week 10

Watch the best plays from Los Angeles Rams quarterback Matthew Stafford's four-touchdown game against the San Francisco 49ers in Week 10 of the 2025 NFL season.

Watch the best plays by the Los Angeles Rams against the San Francisco 49ers in Week 10 of the 2025 NFL season.

Los Angeles Rams running back Kyren Williams rushes for a 7-yard touchdown against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams outside linebacker Jared Verse blocks an extra-point against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams quarterback Matthew Stafford passes a 16-yard touchdown to tight end Colby Parkinson against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams cornerback Emmanuel Forbes scoops up a deflected pass from San Francisco 49ers quarterback Mac Jones for an interception at Levi's Stadium.

Los Angeles Rams quarterback Matthew Stafford fires a 32-yard ball to tight end Terrance Ferguson in San Francisco 49ers territory at Levi's Stadium.

Los Angeles Rams wide receiver Davante Adams catches a 2-yard touchdown against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams outside linebacker Byron Young trips San Francisco 49ers running back Christian McCaffrey for a fourth-down stop at Levi's Stadium.

Los Angeles Rams quarterback Matthew Stafford darts a 15-yard pass to wide receiver Davante Adams against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams quarterback Matthew Stafford sends his 400th career touchdown pass into the hands of tight end Davis Allen against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams running back Blake Corum rushes for 15 yards against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams wide receiver Puka Nacua reels in a pass from quarterback Matthew Stafford for 15 yards against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams linebacker Nate Landman peanut punches the ball loose from San Francisco 49ers wide receiver Juan Jennings for a turnover at Levi's Stadium.

Los Angeles Rams quarterback Matthew Stafford darts a 23-yard pass to wide receiver Davante Adams against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams quarterback Matthew Stafford locates wide receiver Puka Nacua for a 22-yard touchdown against the San Francisco 49ers at Levi's Stadium.

Los Angeles Rams wide receiver Puka Nacua catches a 10-yard pass from quarterback Matthew Stafford for a first down against the San Francisco 49ers.

Los Angeles Rams running back Kyren Williams finds space for a 2-yard rushing touchdown against the San Francisco 49ers at Levi's Stadium.

Watch the best plays from Los Angeles Rams wide receiver Davante Adam's two-touchdown game against the New Orleans Saints in Week 9 of the 2025 NFL season.

Watch the best plays from Los Angeles Rams quarterback Matthew Stafford's four-touchdown game against the New Orleans Saints in Week 9 of the 2025 NFL season.

Watch the best plays from Los Angeles Rams wide receiver Puka Nacua's seven-reception, 95-yard game against the New Orleans Saints in Week 9 of the 2025 NFL season.

Highlights of Los Angeles Rams running back Kyren Williams' best rushes from Week 9 where he totaled 114 yards and a touchdown against the New Orleans Saints.

Watch the best plays by the Los Angeles Rams against the New Orleans Saints in Week 9 of the 2025 NFL season.

Los Angeles Rams cornerback Emmanuel Forbes secures the Rams' win over the New Orleans Saints with an interception off quarterback Tyler Shough.

Los Angeles Rams defensive end Kobie Turner's shoestring tackle on New Orleans Saints quarterback Taysom Hill ends fourth down attempt.