Sean McVay talks about Rams' defense neutralizing opposing offenses' run game, impressions of the 49ers & more

Los Angeles Rams head coach Sean McVay talks about the Rams' defense neutralizing the run game, his impression so far regarding the San Francisco 49ers, and more.

Join us in wishing safety, Kamren Kinchens a happy birthday by watching his first career pick-six from the Los Angeles Rams' matchup against the Seattle Seahawks. To this day, his 103-yard touchdown return is the longest in Rams history!

Watch Los Angeles Rams head coach Sean McVay's victory speech after Sunday's Week 4 win over the Indianapolis Colts.

Check out highlights from Los Angeles Rams wide receiver Puka Nacua's career-high 170-yard game against the Indianapolis Colts.

Los Angeles Rams head coach Sean McVay and quarterback Matthew Stafford discuss the Rams' Week 4 victory over the Indianapolis Colts at SoFi Stadium.

Los Angeles Rams wide receivers Puka Nacua, Davante Adams, Tutu Atwell, and safety Kam Curl react to their win over the Indianapolis Colts at SoFi Stadium.

Watch the best plays from the Los Angeles Rams in Sunday's win over the Indianapolis Colts during Week 4 of the 2025 NFL season.

Troy Santiago y Ricardo López repasan la victoria 27-20 sobre los Colts de Indianapolis. Juntos, hablan de los jugadores que tuvieron un impacto en este partido, las jugadas que cambiaron el rumbo del mismo y cómo esta victoria les prepara para enfrentarse a los 49ers de San Francisco este jueves en primetime.

Los Angeles Rams quarterback Matthew Stafford's best plays from his 375-yard and three touchdown performance vs. the Indianapolis Colts during Week 4 of the 2025 NFL season.

Safety Kam Curl gets his second interception in the Los Angeles Rams' Week 4 matchup off of Indianapolis Colts quarterback Daniel Jones' sideline pass at SoFi Stadium.

Los Angeles Rams outside linebacker Jared Verse strip sacks Indianapolis Colts quarterback Daniel Jones for a loss of 9 yards during their Week 4 matchup at SoFi Stadium.

Los Angeles Rams wide receiver Tutu Atwell with an 88-yard touchdown catch from quarterback Matthew Stafford against the Indianapolis Colts.

Los Angeles Rams wide receiver Puka Nacua dives in the end zone for a touchdown against the Indianapolis Colts at SoFi Stadium.

Los Angeles Rams outside linebacker Jared Verse forces an incompletion by Indianapolis Colts quarterback Daniel Jones during their Week 4 matchup at SoFi Stadium.

Los Angeles Rams safety Jaylen McCollough tackles Indianapolis Colts running back Jonathan Taylor for no gain during Week 4 matchup at SoFi Stadium.

Los Angeles Rams wide receiver Davante Adams makes a 16-yard reception against the Indianapolis Colts during Week 4 matchup at SoFi Stadium.

Los Angeles Rams quarterback Matthew Stafford completes a 23-yard pass to wide receiver Puka Nacua against the Indianapolis Colts during their Week 4 matchup at SoFi Stadium.

Los Angeles Rams wide receiver Davante Adams catches a 10-yard touchdown pass from quarterback Matthew Stafford against the Indianapolis Colts at SoFi Stadium.

Los Angeles Rams outside linebacker Byron Young sacks Indianapolis Colts quarterback Daniel Jones for a loss of 1 yard during their Week 4 matchup at SoFi Stadium.

Los Angeles Rams safety Kam Curl gets his first interception in horns in Rams' Week 4 matchup against the Indianapolis Colts at SoFi Stadium.

On today's Digital Pregame Show presented by Little Ceasars, J.B Long, D'Marco Farr and Maurice Jones-Drew preview the Los Angeles Rams' Week 4 matchup against the Indianapolis Colts. The trio discuss key players, game predictions, and more. Tune in for kickoff at 1:05om PT on FOX.

Los Rams de Los Ángeles se dirigen a Indianapolis para su partido contra los Colts. Mira el tráiler del partido de esta semana para prepararte para el duelo este domingo a las 1:05pm PT en FOX.

Los Angeles Rams head coach Sean McVay talks about injury updates going into the Rams' matchup against the Indianapolis Colts and wide receiver Davante Adams talks about adjusting to their quick turnaround to their primetime matchup against the San Francisco 49ers.

The Los Angeles Rams return to SoFi Stadium to face off against the Indianapolis Colts. Watch this week's game trailer in preparation for Sunday's kickoff at 1:05pm PT on FOX.

Los Angeles Rams offensive coordinator Mike LaFleur and wide receiver Puka Nacua discuss the Rams' versatile run game with running backs Kyren Williams and Blake Corum. Defensive coordinator Chris Shula and outside linebacker Jared Verse talk about what to expect in Sunday's matchup against the Indianapolis Colts.