Rams vs. 49ers Game Center

In celebration of Los Angeles Rams running back Cam Akers' birthday, take a look back and watch his mic'd up game against the San Francisco 49ers Week 18 matchup of the 2021 season.

Rams head coach Sean McVay discusses the latest on the statuses of offensive lineman Andrew Whitworth, safety Taylor Rapp, linebacker Ernest Jones and offensive lineman Joe Noteboom as they begin preparing for the NFC Championship against the 49ers.

The Rams 50/50 Raffle raised a total of $342,975, which set the new NFL record, breaking the previous record of $332,110 set during Super Bowl LIV. 

D'Marco Farr breaks down two of the biggest defensive plays in Week 18's Los Angeles Rams vs. San Francisco 49ers matchup: defensive lineman A'Shawn Robinson's sack & safety Taylor Rapp's interception.

Virtual commemorative tickets are back for the Rams' Wild Card home playoff game against the Cardinals. Here's what you need to know.

Kate Hudson, Tyga, Katie Austin, will.i.am, Leslie Mann, Judd Apatow and many more were at SoFi Stadium for Rams vs. San Francisco 49ers in Week 18. Take a look at photos from the game!

Take a look at photos of Los Angeles Rams Cheerleaders in Week 18 as they cheer on the Rams at SoFi Stadium against the San Francisco 49ers.

Take a look at the best photos from the Los Angeles Rams' Week 18 matchup against the San Francisco 49ers at SoFi Stadium.

Look through photos of fans at SoFi Stadium for Los Angeles Rams vs. San Francisco 49ers.

Esucha cómo Troy Santiago narra la intercepción de Los Angeles Rams DB Jalen Ramsey contra los San Francisco 49ers en la Semana 18 en SoFi Stadium.

Rams wide receiver Cooper Kupp wrapped up the 2021 regular season making one last piece of history. 

"Seguiremos adelante de la manera correcta", dice Sean McVay de cara a los playoffs, donde Los Ángeles queda sembrado como No. 4 de la NFC

Key quotes and notes from Rams head coach Sean McVay, cornerback Jalen Ramsey, quarterback Mathew Stafford and wide receiver Cooper Kupp's postgame press conferences following their 27-24 overtime loss to the 49ers on Sunday at SoFi Stadium.

Watch the best plays by Los Angeles Rams wide receiver Cooper Kupp's 136-yard game from Week 18 of the 2021 season.

Rams WR Cooper Kupp discusses what he took away from the offense's performance in Sunday's 27-24 overtime loss to the 49ers.

Rams QB Matthew Stafford discusses what he took away from his individual performance and the offense's overall performance in Sunday's 27-24 overtime loss to the 49ers.

Rams DB Jalen Ramsey discusses what he took away from the defense's performance in Sunday's 27-24 overtime loss to the 49ers and the unit adjusting to him becoming the on-field defensive signal-caller in wake of S Jordan Fuller's ankle injury late in the game.

Rams head coach Sean McVay discusses the team's 27-24 overtime loss to the 49ers on Sunday, including how the second half unfolded and the team's new playoff path because of the result.

The Rams fell to the 49ers 27-24 in overtime in the regular season finale. 

Los Angeles Rams wide receiver Cooper Kupp secures quarterback Matthew Stafford's 30-yard sideline pass for a critical first down against the San Francisco 49ers in the Week 18 matchup at SoFi Stadium.

Los Angeles Rams wide receiver Cooper Kupp secures the go-ahead touchdown in the Rams vs. San Francisco 49ers Week 18 matchup at SoFi Stadium.

The Los Angeles Rams ILB Troy Reeder sacks San Francisco 49ers quarterback Jimmy Garoppolo in Week 18 at SoFi Stadium.

Los Angeles Rams defensive lineman A'Shawn Robinson sacks San Francisco 49ers quarterback Jimmy Garoppolo in the Week 18 matchup at SoFi Stadium.

Los Angeles Rams tight end Tyler Higbee's wide-open touchdown in the Rams vs. San Francisco 49ers Week 18 matchup at SoFi Stadium.

The Los Angeles Rams take on the San Francisco 49ers for Week 18 at SoFi Stadium. Take a look at photos from the matchup!