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The Rams host the 49ers at SoFi Stadium in Week 2. Kickoff on Sunday is scheduled for 1:05 p.m. pacific time on FOX.

Ahead of the game, theRams.com examines 3 Keys to Winning for the Rams, powered by The Wallace Firm:

1. Protect Stafford

The 49ers defense sacked Steelers quarterback Kenny Pickett five times last week and has one of the most physical fronts in the NFL. Winning that battle in the trenches is not only important to giving quarterback Matthew Stafford a clean pocket to operate in, but also to be efficient on early downs by creating lanes for the run game.

2. Pressure Purdy

Second-year quarterback Brock Purdy did well playing within the timing and rhythm of San Francisco's offense in Week 1 – as he did toward the end of last season – but is also capable of making off-schedule plays.

Even when pressured, he can still get rid of the ball quickly. Not only will bringing it to disrupt that timing and rhythm still be critical for Los Angeles' defense, so will the secondary when it comes to defending those passes and ensuring the intended targets don't gain yards after the action.

3. Contain 49ers' offensive playmakers

There are multiple, between tight end George Kittle, wide receivers Brandon Aiyuk and Deebo Samuel, and running back Christian McCaffrey.

Samuel and McCaffrey get used in multiple ways, so it will be especially important to monitor where they line up at all times on Sunday afternoon.

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